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Caffeine is associated with an increase of vasomotor symptoms in postmenopausal women


Researchers have assessed the association between Caffeine intake and menopausal symptom bother, particularly vasomotor symptoms.

A cross-sectional survey was conducted using the Menopause Health Questionnaire, which is a comprehensive survey of menopause-related health information.

Questionnaires were completed by 2,507 consecutive women who presented with menopausal concerns at the Women's Health Clinic at Mayo Clinic ( Rochester, MN, USA ) in the period 2005-2011.

Data from 1,806 women who met all inclusion criteria were analyzed. Menopausal symptom ratings were compared between women who used Caffeine and women who did not use Caffeine using two-sample t test and analysis of covariance, with smoking and menopause status included as covariates.
In all cases, two-tailed P less than 0.05 was considered statistically significant.

Caffeine use was positively associated with mean vasomotor symptom scores ( 2.30 vs 2.15; P=0.011 ).

This finding remained significant after adjustment for menopause status and cigarette smoking ( P=0.027 ).

In conclusion, Caffeine use is associated with greater vasomotor symptom bother in postmenopausal women. ( Xagena )

Faubion SS et al, Menopause 2014; Epub ahead of print

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